Investigating the role of beta1 integrin in hepatic stellate cell activation and liver fibrosis

Liver fibrosis is characterised by progressive deposition of type 1 collagen-rich extracellular matrix in response to iterative liver injury. The progressive accumulation of scar tissue within the liver predisposes to the development of hepatocellular carcinoma, and ultimately leads to organ failure...

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Bibliographic Details
Main Author: Martin, Katherine
Published: University of Manchester 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668552