Pathological mechanisms underpinning amelogenesis imperfecta in mice carrying an amelogenin mutation
Mice carrying a Y64H amelogenin mutation phenotypically mimic human amelogenesis imperfecta. Affected ameloblasts are characterised by the presence of abnormal cytoplasmic vesicles of retained amelogenin. Protein-protein binding studies using recombinant wild type and Y64H amelogenin revealed that t...
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University of Leeds
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668768 |