An implantable hydrogel for the delivery of cisplatin and the ex vivo neurotoxic, neuromyopathic and cardiotoxic activity of platinum-based anticancer drugs and macrocyclic drug delivery systems

Cisplatin iscurrently aleading anticancer drug used in the treatment of various cancers. Its clinical use, however, is limited by its poor bioavailability, its undesirable toxic side effects profile and by the ability of certain tumours to develop cisplatin resistance. A method that may overcome the...

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Bibliographic Details
Main Author: Oun, Rabbab Hadi
Published: University of Strathclyde 2015
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668876