Receptor revision and somatic hypermutation-mechanisms of B cell diversification
The production of high affinity antibodies is critical for providing effective protection against microbial agents. During the T cell dependent response to antigen, secondary diversification of the B cell receptor occurs. This provides a varied pool of B cells which can be selected and expanded resu...
| Main Author: | |
|---|---|
| Published: |
University of Edinburgh
2002
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669285 |