Receptor revision and somatic hypermutation-mechanisms of B cell diversification
The production of high affinity antibodies is critical for providing effective protection against microbial agents. During the T cell dependent response to antigen, secondary diversification of the B cell receptor occurs. This provides a varied pool of B cells which can be selected and expanded resu...
Main Author: | Gallagher, Aoife M. |
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Published: |
University of Edinburgh
2002
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669285 |
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