HSV-1 amplicons, a non-integrating, high transgene capacity tool for the generation and differentiation of induced pluripotent stem cells

Induced pluripotent stem (iPS) cells are valuable for generating patient-specific disease models. Many reprogramming systems have been developed however some technological concerns remain including insertional mutagenesis caused by integrating viruses, low efficiency and low transgene capacity. Herp...

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Bibliographic Details
Main Author: Popplestone, Anna
Other Authors: James, William ; Wade-Martins, Richard
Published: University of Oxford 2013
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669863