Identification and functional analysis of MAP4K3 as a novel regulator of autophagy

The cell survival pathway autophagy, sequesters and degrades long lived and damaged proteins, recycling for reuse as biosynthetic building blocks. Autophagy is often dysregulated in disease pathologies, evidences shows both loss or gain of autophagy function can provide survival advantage. Constitut...

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Bibliographic Details
Main Author: Fee, Emily
Published: Queen's University Belfast 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676466