Towards the total synthesis of nakadomarin A

Nakadomarin A was first isolated from the sponge Amphimedon sp. by Kobayashi and co-workers in 1997. The structure showed a unique hexacyclic skeleton consisting of 5-, 6-, 8- and 13-membered rings. This natural product shows cytotoxicity, antimicrobial and inhibitory activities. The challenging str...

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Bibliographic Details
Main Author: Xu, Chao
Published: University of Glasgow 2015
Subjects:
547
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676565