Towards the development of caspase-3/7 inhibitor(s) for in vivo PET imaging of cancer apoptosis

The ability to image caspase activation provides a powerful tool for the evaluation of the oncologic therapeutic response via the apoptotic cascade. Research efforts have focused on the development of radiolabelled non-peptidyl caspase inhibitors to be utilised for imaging purposes. Isatin sulfonami...

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Bibliographic Details
Main Author: Udemba, Angela
Other Authors: Fuchter, Matthew ; Aboagye, Eric
Published: Imperial College London 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676759