A search for novel biomarkers predicting toxicity and response to thiopurine treatment in patients with inflammatory bowel disease
The thiopurines, mercaptopurine (MP) and its pro-drug azathioprine (AZA), are the first line immunomodulators used in the management of inflammatory bowel disease (IBD). Unfortunately, 30 - 40% of patients are unable to derive benefit from these medicines as a result of drug toxicity or treatment no...
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King's College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676959 |