Genetic mechanisms regulating neural stem cell self-renewal and differentiation in the central nervous system of Drosophila

Asymmetric cell division plays a fundamental role in maintaining a balance between stem cell self-renewal and differentiation. A failure of this balance results in over-proliferation of stem cells, which could eventually lead to neoplastic over-growth and mestasis, i.e. tumourigenesis. Key component...

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Bibliographic Details
Main Author: Kim, Dongwook
Other Authors: Hirth, Frank
Published: King's College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677019