On the role of prelamin A in the heart

Prelamin A is one of two protein products of the LMNA gene and undergoes proteolytic processing to become mature lamin A, a crucial protein for nuclear envelope structure and function. Evidence suggests that when this process is hindered, resulting in accumulation of prelamin A, premature ageing dis...

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Bibliographic Details
Main Author: Brayson, Daniel James
Other Authors: Shanahan, Catherine Mary ; Shah, Ajay Manmohan
Published: King's College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677032