Targeting Ras GTPases in murine models of renal fibrosis

End stage kidney disease (ESKD) affects over 5300 people. The progression of chronic kidney disease (CKD) to ESKD is characterised by cytokine stimulation, leading to the activation of myofibroblasts, resulting in fibrosis. Kirsten rat sarcoma (KNRas) has a key role in the proliferation of renal fib...

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Bibliographic Details
Main Author: Newbury, Lucy Jade
Other Authors: Hendry, Bruce Melville ; Sharpe, Claire Catherine
Published: King's College London (University of London) 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677169