The dysregulation of microRNAs due to mutant p53R172H expression in a mouse model of pancreatic ductal adenocarcinoma

Pancreatic cancer is one of the most aggressive of human malignancies, with incidence almost equalling mortality. The main reason for the poor prognosis is that the majority of pancreatic cancer cases are not diagnosed until the disease has metastasised. Mutations to p53 have been shown to have gain...

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Bibliographic Details
Main Author: Godfrey, Jack David
Other Authors: Bushell, Martin ; Willis, Anne
Published: University of Leicester 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677404