Gene delivery via polymeric microneedles : the use of a novel amphipathic peptide

The focus of this thesis was to develop a two-tier delivery system suitable for DNA delivery in vivo. Firstly, 4 peptides were investigated to determine their ability to overcome the intracellular and extracellular barriers which inhibit the expression of 'naked' DNA when administered in v...

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Bibliographic Details
Main Author: McCaffrey, J.
Published: Queen's University Belfast 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679228