Gene delivery via polymeric microneedles : the use of a novel amphipathic peptide
The focus of this thesis was to develop a two-tier delivery system suitable for DNA delivery in vivo. Firstly, 4 peptides were investigated to determine their ability to overcome the intracellular and extracellular barriers which inhibit the expression of 'naked' DNA when administered in v...
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Queen's University Belfast
2014
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679228 |