Carbon-halogen bond formation in enzymes
SyrB2, a non-haem Fe halogenase first discovered in 2005, carries out a cryptic chlorination during the biosynthesis of syringomycin E in the bacterium Pseudomonas syringae. SyrB2 chlorinates its native substrate, l-Threonine (Thr), at an unactivated methyl group. It is able to activate this highly...
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University of Glasgow
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679578 |