Studies of the protein tyrosine phosphatase PTPN22/Lyp in Ptpn22 deficient mice
An R620W polymorphism in the haematopoietic protein tyrosine phosphatase PTPN22 increases susceptibility to a number of autoimmune diseases, including rheumatoid arthritis. PTPN22 is a negative regulator of immune cell signalling and its role has been best characterised in T cell receptor (TCR) sign...
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King's College London (University of London)
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679782 |