The effects of hypercapnia on CFTR-dependent HCOb3p-s secretion in human airway epithelia

Hypercapnia is clinically defined as an arterial blood partial pressure of CO2 of above 40mm Hg and is a symptom of chronic lung disease. In renal epithelia, hypercapnia can reduce agonist-stimulated cAMP levels and impair regulation of cAMP-dependent ion transporters. In the airways, elevations in...

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Bibliographic Details
Main Author: Turner, Mark John
Published: University of Newcastle upon Tyne 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680345