Analysis of aldehyde detoxification mechanisms and the effects of a novel aldehyde scavenging drug in experimental diabetic retinopathy

Recent studies have identified that retinal Muller cells accumulate the acrolein (ACR)-derived protein adduct FDP-lyslne during diabetes. The phenomenon has been linked with the dysfunction of these calls in the early stages of diabetic retinopathy. The current project investigates the processes und...

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Bibliographic Details
Main Author: McDowell, Rosemary Eleanor
Published: Queen's University Belfast 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680435