The use of in vitro models to study drug permeability and irritancy in the presence of mucus

Mucus overproduction is an important feature of chronic inflammatory airway diseases including cystic fibrosis, chronic bronchitis, bronchiectasis and severe asthma. Inhaled drugs are often delivered to such diseased airways where mucus hypersecretion is likely to alter the deposition pattern of the...

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Bibliographic Details
Main Author: Lee, Diane F.
Published: University of Brighton 2015
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681175