Tryptophan oxidation by the heme-containing dioxygenases

In biology, the kynurenine pathway is the major degradation pathway of tryptophan (L-Trp). The first and rate-limiting step is the oxidation of L-Trp to N-formylkynurenine (NFK). The mechanism of this oxygen-dependent reaction has not been established, but is catalysed by two heme-containing dioxyge...

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Bibliographic Details
Main Author: Booth, Elizabeth Suzanne
Other Authors: Raven, Emma ; Handa, Sandeep
Published: University of Leicester 2016
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682409