The effect of homocysteine on the oxidative folding pathway in the ER

Upon translation into the endoplasmic reticulum (ER), ER resident proteins, and those destined for the secretory pathway, must be correctly folded into their native structure to be functional. During folding, many proteins must form disulphide bonds, a process facilitated by protein disulphide isome...

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Bibliographic Details
Main Author: Appleby, Alice Jo
Published: Durham University 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683956