Role of ubiquitin-modifying enzymes in regulating the endothelial response to VEGF-A

Cell surface receptors undergo degradation but the biochemical basis for such control remains poorly defined. Endothelial cells express vascular endothelial growth factor receptor 2 (VEGFR2) which binds to circulating VEGF-A, stimulating signal transduction and new blood vessel sprouting i.e. angiog...

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Bibliographic Details
Main Author: Smith, Gina Anne
Other Authors: Ponnambalam, Sreenivasan ; Harrison, Michael ; Tomlinson, Darren
Published: University of Leeds 2016
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684542