In vitro and in vivo characterisation of the mechanisms involved in opioid-induced tolerance
Opioid analgesics are the leading class of prescription drugs that cause unintentional overdose deaths via respiratory depression. Poly-drug use is a common cause of death, with ethanol detected in approx.. 50% of heroin-related cases. Tolerance can be reversed by low concentrations of ethanol in lo...
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University of Bristol
2015
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684743 |