Design, characterisation and functional evaluation of a ɑ-helical barrels

The de novo design of active biomolecules, where both structure and function are constructed from first principles, requires the precise positioning of chemical functionality within stable and thoroughly characterised scaffolds. The first hexameric coiled coil, CC-Hex, is a homo-hexameric peptide as...

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Bibliographic Details
Main Author: Burton, Anthony J.
Published: University of Bristol 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686247