Optimisation of T cell receptors using in vivo recombination and selection
The αβT cell receptor (TCR) orchestrates immunity through the recognition of peptides, derived from degraded proteins, presented on major histocompatibility complex (MHC) molecules. The remarkable ability of the receptor to respond to a vast plethora of antigens is driven by V(D)J recombination, a p...
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Imperial College London
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686344 |