Structural and biophysical investigations of two negative regulators of DNA replication initiation in Bacillus subtilis, YabA and SirA

DNA replication initiation is strictly controlled to maintain chromosome copy number. Over- or under-replication of an organism's genome is detrimental to survival, thus initiation events are tightly regulated to ensure only one round of DNA replication occurs per cell cycle. In prokaryotes, DN...

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Bibliographic Details
Main Author: Jameson, Katie H.
Other Authors: Wilkinson, A. J.
Published: University of York 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686534