Galectin-3 and the development of autosomal recessive polycystic kidney disease

Galectin-3 is a β-galactoside-binding lectin implicated in renal collecting duct development and differentiation. Autosomal recessive polycystic kidney disease (ARPKD) affects 1 in 20,000 humans, and is characterised by cyst development from collecting ducts. Galectin-3 retards cystogenesis in at le...

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Bibliographic Details
Main Author: Chiu, Miliyun
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686669