A computational model of thiopurine metabolism
A computational model of thiopurine metabolism The thiopurines, azathioprine, mercaptopurine (MP) and thioguanine are used as immunosuppressants and in the treatment of leukaemia. These drugs undergo extensive metabolism to form their cytotoxic metabolites that correlate with drug efficacy and the l...
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University of Newcastle upon Tyne
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686861 |