The role of Hippo signalling in cell fate decisions in mouse embryonic stem cells and pre-implantation development

The Hippo signalling pathway is a conserved kinase cascade involved in the regulation of tissue growth and organ size. Activation of the Hippo pathway through multiple upstream inputs results in phosphorylation and inactivation of the transcriptional co-activator, Yes associated protein (Yap). While...

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Bibliographic Details
Main Author: Brimson, Christopher A.
Other Authors: Munoz-Descalzo, Silvia ; Tosh, David
Published: University of Bath 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687385