Development of aza-Heck cyclisations and cascades for the synthesis of nitrogen heterocycles
Palladium- and copper-catalysed aza-Heck cyclisations of oxime esters with pendant olefins, have been developed for the synthesis of chiral nitrogen heterocycles. Initial studies explored palladium-catalysed cyclisations onto 1,1-disubstituted alkenes to afford α,α-disubstituted dihydropyrroles. A w...
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University of Bristol
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687438 |