Modulation of innate immune signaling by the small T antigen of Merkel cell polyomavirus, the causative agent of Merkel cell skin cancer
Merkel cell Polyomavirus (MCPyV) is implicated in the pathogenesis of Merkel cell carcinoma (MCC), a rare and highly aggressive neuroendocrine skin cancer, through expression of two oncoproteins, small T antigen (sT) and large T antigen (LT). MCPyV sT expression is essential for cell transformation,...
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University of Leeds
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689262 |