Design, synthesis and biological evaluation of DNA gyrase and topoisomerase IV inhibitors as novel antibacterials
The spread of antibiotic resistance is a great threat to medicine. We are in desperate need of new antibiotics to replace those for which resistance is widespread. The bacterial type two topoisomerases, DNA gyrase and topoisomerase IV, are well validated antimicrobial targets. The fluoroquinolone an...
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University of Leeds
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689277 |