The molecular control of beta cell function by insulin and hypoxia cellular signalling pathways

The molecular control of beta cell function by insulin and hypoxia cellular signalling pathways

This thesis reports the investigation of the role of the insulin receptor substrate 2 (Irs2) and von Hippel-Lindau (Vhl) genes in B-cell function, using the cre-loxP system to delete these genes in the pancreas of mice. Pancreatic 8-cells sense and respond to the metabolic status of the body via cel...

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Bibliographic Details
Main Author:	Cantley, J. M.
Published:	University College London (University of London) 2007
Subjects:	612.3
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689441

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