Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer : effect of oestrogen receptor
Background: HER2 gene amplification and protein overexpression defined as HER2 positivity (HER2+) breast cancer (BC) is encountered in 15-25% of cases and is characterised by an aggressive behaviour and poor outcome. Despite the high clinical efficacy of anti-HER2 targeted therapy, the response and...
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University of Nottingham
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689766 |