Developing bone marrow derived cell therapies for cerebellar disorders

Friedreich's ataxia (FRDA) is a neurodegenerative disorder, which is progressive and currently incurable. The genetic defect causes a reduced expression of the mitochondrial protein, frataxin. Oxidative damage and mitochondrial dysfunction are key factors of this disorder. A potential strategy...

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Bibliographic Details
Main Author: Dey, Rimi
Published: University of Bristol 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.691249