The interaction between factor H and factor H binding protein in susceptibility to Meningococcal disease
Neisseria meningitidis recruits the complement regulator, factor H (fH), to its surface via factor H binding protein (fHbp), enabling it to evade the immune system. fHbp was included in vaccines prior to it being known that fHbp bound fH, potentially masking epitopes and reducing immunogenicity. fH...
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Imperial College London
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.692273 |