Model based process design for a monoclonal antibody-producing cell line : optimisation using hybrid modelling and an agent based system

The biopharmaceutical industry has seen rapid growth over the last 10 years in the area of therapeutic medicines. These include products such as monoclonal antibodies (mAbs) produced using mammalian cell lines such as Chinese Hamster Ovary (CHO). In order to comply with the regulatory authority (FDA...

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Bibliographic Details
Main Author: Green, Amy Jane
Published: University of Newcastle upon Tyne 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.692658