Investigating the transcriptional correlates of cognition in the heterozygous HdhQ150 mouse model of Huntington's disease

Huntington’s disease (HD) is a progressive autosomal dominant neurodegenerative disorder caused by expansion of a trinucleotide CAG repeat in the Huntingtin gene (HTT) on chromosome 4. HD symptomatology is characterised by a triad of motor, cognitive, and psychiatric disturbances, as well as transcr...

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Bibliographic Details
Main Author: Scoberg-Evans, Jordan
Published: Cardiff University 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693427