DISC-dependent versus DISC-independent aspects of non-apoptotic TRAIL signalling

The Tumour Necrosis Factor (TNF) superfamily member TNF-related apoptosis- inducing ligand (TRAIL) can selectively induce apoptosis in a wide variety of tumour cells in vivo without causing toxicity to normal cells. Consequently, these findings have triggered the design of novel TRAIL-based cancer t...

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Bibliographic Details
Main Author: Prieske, Silvia
Other Authors: Walczak, Henning
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693888