Investigating the interaction of the PKB PH domain with inositol phosphate-based compounds
Protein kinase B (PKB) plays a key role in the phosphoinositide 3-kinase pathway, one of the most frequently activated proliferation pathways in cancer. A key stage in this pathway is PKB's translocation to the plasma membrane, which is driven by direct interaction of PKB's pleckstrin homo...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693911 |