Phenotypic characterisation of the PLM3SA mouse expressing unphosphorylatable phospholemman

Cardiac Na+/K+ ATPase plays a pivotal role in maintaining the Na+ transmembrane gradient which is essential for normal cardiac function. Elevation of intracellular Na+ ([Na+]i) is a key contributor to contractile and electrical dysfunction in a variety of pathologies. Phospholemman (PLM), is the car...

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Bibliographic Details
Main Author: Aughton, Karen Louise
Other Authors: Shattock, Michael Jonathan
Published: King's College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695710