The effect of anaesthetic and analgesic agents on glutamate uptake and release from rat neuronal preparations
In rat cerebrocortical and cerebellar synaptosomes the uptake of [3H]L-glutamate was time-, concentration-(Km=-8.6 and ~2.2M respectively), Na+-dependent and L-trans-PDC sensitive. In general the uptake mechanism was insensitive to clinically relevant concentrations of anaesthetics.;Perfused rat cer...
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University of Leicester
1997
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696210 |