Molecular recognition within the minor groove of the DNA double helix
This thesis describes the synthesis of two nucleoside analogues with potential hydrogen bond acceptor sites removed. The effect that these compounds have on the sequence specific binding of distamycin to (AT) sequences and the stability of DNA double helices has been investigated. The approach taken...
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University of Leicester
1997
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696278 |