Approaches to the study of protein secretion in yeast

Mutants of the yeast Saccharomyces cerevisiae that showed enhanced secretion yield of a mini-proinsulin reporter protein were isolated, following random mutagenesis, via a footprint assay screen. Three such mutants, exhibiting a 2-3 fold increase in secretion yield, were shown to contain recessive m...

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Bibliographic Details
Main Author: Gill, Bhupinder
Published: University of Leicester 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696302