Involvement of ICE-like protease(s) in TGF-beta 1 induced apoptosis in hepatocytes

Internucleosomal DNA cleavage is often regarded as the biochemical hallmark of apoptosis and can be reproduced in vitro in rat liver nuclei. This chromatin cleavage in rat liver nuclei was further characterised and studies described in this thesis showed that the DNA was initially cleaved into 700kb...

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Bibliographic Details
Main Author: Inayat-Hussain, Salmaan H.
Published: University of Leicester 1997
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696361