Scrapie associated fibrils and polymeric PrP
The conversion of PrPC, the normal form of the prion protein, to PrPSc, the protease-resistant disease specific form, is central to the pathogenesis of the transmissible spongiform encephalopathies. The mechanism underlying this conformational change remains elusive but the demonstration that PrPSc...
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University of Leicester
1998
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696425 |