Investigating the mechanism and energy coupling of DNA gyrase
DNA gyrase is the bacterial type II topoisom erase w hich couples the free energy o f ATP hydrolysis to the introduction of negative supercoils into DNA. The active enzym is composed of two GyrA and two GyrB subunits forming an A2B2 complex. The specific supercoiling activity of GyrB was found to be...
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University of Leicester
1998
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696426 |