Activation and subcellular localisation of caspases in wild-type p53-induced apoptosis in vitro and fas-induced apoptosis in vivo
Despite previous studies demonstrating caspase-3 processing following treatment with DNA-damaging agents, there has been no direct evidence of p53WT-induced caspase activation. In this thesis an in vitro temperature-sensitive cell system was employed to study the effects of p53WT. Consistent with pr...
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University of Leicester
1998
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696518 |