The activation of guanine nucleotide binding proteins by muscarinic acetylcholine receptor subtypes
Agonist-stimulation of human recombinant M1, M2, M3 and M4 receptors, expressed in Chinese hamster ovary cells, was investigated at the level of G protein activation. Functional responses were determined by a number of methods including [35S]-GTPS binding in membranes using both filtration-based and...
| Main Author: | |
|---|---|
| Published: |
University of Leicester
1999
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696604 |